Low and High Radio-Iodine-131 Doses in Postoperative Ablation in Differentiated Thyroid Carcinoma

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Low and High Radio-Iodine-131 Doses in Postoperative Ablation in Differentiated Thyroid Carcinoma

The goals of post-surgical RAI therapy in patients with differentiated DTC are to ablate residual normal thyroid tissue that may facilitate surveillance,) Also the potential tumoricidal effect on residual microscopic RAI-avid disease, and to provide a posttreatment whole-body scan that may reveal undetected local or distant metastases.Although, these goals are important, the ultimate endpoint o...

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Postoperative radioactive iodine-131 ablation is not necessary among patients with intermediate-risk differentiated thyroid carcinoma: a population-based study.

OBJECTIVE To assess the effectiveness of radioactive iodine (RAI) ablation among patients with intermediate-risk differentiated thyroid cancer (DTC) following surgery. SUBJECTS AND METHODS This population based study obtained information from the Surveillance, Epidemiology, and End Results (SEER) Program Research Data (1973-2013). National Cancer Institute, DCCPS, Surveillance Research Progra...

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Thyroglobulin-guided (131)I ablation in low-risk differentiated thyroid carcinoma: is the yardstick accurate enough?

To the Editor: Vaisman and colleagues recently suggested to rule out I ablation in patients with low-risk differentiated thyroid carcinoma (DTC) having negative neck ultrasound, negative thyroglobulin (Tg) antibodies (TgAb), and serum rhTSH-stimulated Tg levels from <1 to 5 ng/mL, measured 3 months after thyroidectomy and selective central compartment neck dissection. In our opinion, however, s...

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Prototype imaging protocols for monitoring the efficacy of iodine-131 ablation in differentiated thyroid cancer.

Whole-body and single photon emission tomography (SPET) images during sodium iodide-131 (Na131I) ablation are useful to confirm the efficacy of ablation using 131I imaging. However, there have been no attempts to improve the quality of 131I imaging. We therefore investigated imaging protocols for 131I imaging in differentiated thyroid cancer (DTC). Phantoms containing 131I were used to simulate...

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[Postoperative radioiodine ablation in patients with low risk differentiated thyroid carcinoma].

Most patients with newly diagnosed differentiated thyroid carcinoma have tumors with low risk of mortality and recurrence. Standard therapy has been total or near total thyroidectomy followed by postoperative radioiodine remnant ablation (RRA). Although RRA provides benefits, current clinical guidelines do not recommend it universally, since an increase in disease-free survival or a decrease in...

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ژورنال

عنوان ژورنال: The Egyptian Journal Nuclear Medicine

سال: 2015

ISSN: 2536-9113

DOI: 10.21608/egyjnm.2015.5444